Background and objective : Low blood pressure and Muscle cramps are common complications of Hemodialysis. One approach that has recently been proposed to prevent this complication is the combination of sodium and ultrafiltration. The purpose of this study was to investigate the effect of of sodium and ultrafiltration profile on some of the common complications during Hemodialysis.

  Material and Methods: In this crossover clinical trial study, 22 Hemodialysis patients referred to Panje-­Azar Hospital in 2012 were divided randomly into two groups. For each group, two treatment protocols were conducted, six hemodialysis sessions. The intervention protocol was a linear sodium dialysate and linear ultrafiltration. In routine Protocol, both sodium dialysate and ultrafiltration were considered constant. Using chi-square test and relative risk, the data was analyzed (P<0.05).

  Results: The mean age is 54.73 ± 11.21 year and 59.1% of them are females. The incidence of hypotension and muscle cramps in the experimental protocol procedure is significantly decreased compared with that of control group (P<0.05), but the incidence of headache and vomiting is not significant (P<0.05).

  Conclusion: Because sodium and ultrafiltration profile is simple and cost-free and reduces the incidence of complications during dialysis, we recommend using sodium and UF profile instead of routine one.

  Background and Objective: Hypertension in patients with non-alcoholic fatty liver disease is the main cause of cardiovascular disease . The present study aimed to determine the effect of Berberis vulgaris fruit extract on blood pressure and weight in patients with non-alcoholic fatty liver disease.

  Material and Methods: This clinical trial was conducted in 2011 on 80 patients with non-alcoholic fatty liver disorder, including 32 males (40%) and 48 females (60%), who were randomly assigned into case and control group. The case group were given two capsules (750 mg) including berberis vulgaris extract every day for three months, while the subjects of control group treated by placebo. Blood pressure and weight of baseline and those of after three month were assessed and analyzed by SPSS software Ver.17, using paired t-test and independent t-test (p≤0.05).

  Results: the mean of weight decreased from 80.23±11.68 (baseline) to 78.71±11.31 (End of the third month), which was statistically significant compared to control group (P<0.001). The Mean of systolic and diastolic blood pressure was significant compared to control group. (p<0.05).

  Conclusion: Considering the significant decrease in weight and blood pressure, further studies with larger sample size are needed to generalize crucially the results. This extract can be introduced to treat overweight and hypertension in patients with non-alcoholic fatty liver disease.