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Sedighe Rezaie-Chamani, Mona Rahnavardi, Shadi Sabetghadam, Sahar Mahbubinejad, Azizeh Farshbaf-Khalili, Nazanin Rezaie,
Volume 17, Issue 1 (4-2020)
Abstract

Background: Sexuality is an important and inseparable part of the life of every woman. Female sexual dysfunction (FSD) has a major influence on quality of life and can lead to personal distress and anxiety. This study aimed to determine the prevalence of sexual dysfunction and predisposing factors in women.
Methods: This cross-sectional study was carried out on 400 outpatient women aged 15-49, who had a health record in the health care centers of Rasht, Iran during 2015-2016. Samples were selected through multi-stage cluster sampling method. Data collection tool included demographics and reproductive information, the standard questionnaire of female sexual function index (FSFI). Multivariate linear regression analysis was used to determine the predictors of sexual dysfunction in SPSS 13.
Results: The mean±SD score of total FSFI was 28.14±3.82, ranging from 2 to 36. The frequency of sexual dysfunction was 34.3% in total. Multivariate linear regression analysis showed a significant correlation between FSFI and some factors including age, education level, age at menarche, frequency of sex, and knowledge on sexual function. These factors accounted for 12% of the variance in the sexual function index of women.
Conclusions: Considering the critical impact of sexual function on the health of couples, paying attention to sexual function in women and its predictors are important to help and plan prevention programs.
 
Mahdis Chegini, Khadije Hajizade, Azize Farshbaf, Fateme Lalooha, Mahnaz Shahnazi,
Volume 20, Issue 1 (4-2023)
Abstract


Background: Food intake and metabolism might play central roles in causing and treating menstrual disorders. Vitamin D may lead to the improvement of folliculogenesis through anti-Mullerian hormone (AMH). This study aimed to compare the effect of vitamin D intake with that of the combined oral contraceptive (COC) capsules on ovulatory dysfunction.
Methods: This study was conducted on 60 eligible women referred to Kowsar Qazvin Hospital with a complaint of abnormal uterine bleeding (AUB). They had a history of excessive, long, and irregular bleeding. The participants in the control and intervention groups received 1 oral LD capsule and a combination of vitamin D and LD capsules on a daily basis for 3 months, respectively. The menstrual bleeding volume, the number of menstrual days, and the menstrual cycle length were evaluated before, during, and after the intervention. The Mann-Whitney U test, Friedman test, independent t test, and Cochran Q test were used in SPSS version 24 for data analysis. P values less than 0.05 were considered statistically significant.
Results: The menstrual bleeding intensity decreased significantly in the intervention group (vitamin D–LD capsule; P = 0.001). Over time, both intervention and control groups showed a significant improvement in the number of menstrual days and menstrual cycle length, resulting in a more normal menstrual cycle. However, these 2 parameters remained more natural in the intervention group, a finding which did not indicate any significant differences.
Conclusion: Vitamin D can be used along with LD capsules as a supplementary treatment to lessen menstrual bleeding intensity.

Faride Majdi , Azizeh Farshbaf-Khalili , Mohammadreza Mirzayi , Parvin Hakimi , Khadije Hajizadeh, Mahnaz Shahnazi ,
Volume 22, Issue 2 (6-2025)
Abstract

Background: Polycystic Ovary Syndrome (PCOS) is one of the most significant reproductive and endocrine disorders in women. This study aims to assess the impact of nettle extract on both clinical and paraclinical symptoms in women with PCOS.
Methods: This Triple-Blind Randomized Controlled Clinical Trial involved 60 women (n = 30 per group) aged 18 to 45, all diagnosed with PCOS based on definitive diagnostic criteria in Tabriz, Iran. Participants were randomly assigned in a 1:1 ratio using block sizes of 4 and 6 into two groups: an intervention group (receiving 500 mg of oral nettle extract containing flavonoids, tannins, and sterols daily for three months) and a control group (receiving combined oral contraceptives [COCs] for three months). Independent t-test and ANCOVA test were used in SPSS version 24 for data analysis. A p-value of <0.05 was considered statistically significant.
Results: The study showed that after the intervention, there were no statistically significant differences between the nettle extract group and the control group regarding mean levels of dehydroepiandrosterone sulfate (P=0.197), total testosterone (P=0.24), follicle-stimulating hormone (FSH) (P=0.549), luteinizing hormone (LH) (P=0.398), hirsutism score (P=0.149), or duration of menstrual bleeding (P=0.982), based on ANCOVA adjusted for baseline values, education level, and number of pregnancies. However, the two groups exhibited statistically significant differences in fasting blood glucose levels (P=0.020), intervals between menstrual bleeding (days) (P=0.031), and menstrual bleeding intensity (P = 0.008).
Conclusion: The findings indicate that nettle extract is as effective as low-dose oral contraceptive pills in reducing levels of dehydroepiandrosterone, total testosterone, follicle-stimulating hormone (FSH), and luteinizing hormone (LH), as well as in decreasing hirsutism scores and the duration of menstrual bleeding. Midwives can use nettle extract, which is a cheap, easy, and non-invasive method to improve PCO symptoms.

 


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