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Comparison of Analgesic Effect of Agnogol with Mefenamic Acid in the Treatment of Primary Dysmenorrhea
Masoumeh Delaram, Zahra Sadeghian , Neda Parvin, Afsaneh Kazemiyan, Sahand Shams,
Volume 12, Issue 1 (4-2015)
Abstract

Background and Objective: Primary dysmenorrhea is one of the most common complaints among women in reproductive age in that about half of young women suffer from dysmenorrhea. Nowadays, many people have a tendency to use a traditional medicine for dysmenorrhea. Hence, we aimed to compare the analgesic effect of Agnogol and Mefenamic acid in the treatment of primary dysmenorrhea. 

Material and Methods: This clinical trial was conducted on 44 women with primary dysmenorrhea referred to Hajar hospital in Shahrekord. The participants were randomly allocated to two groups of Agnogol (n=23) to use one 3.2 mg Agnogol pill for three times a day and Mefenamic Acid (n=21) to use 250 mg Mefenamic acid every 8 hours a day for three days. The pain severity was detected by Visual Analogue Scale. We used Independent and Paired t test for comparing the means of quantitative variables and Chi Square for qualitative variables ( P<0.05 ). 
Results: Considering age, menstrual duration, menstrual interval, and pain severity score, there was no significant difference in two groups at the beginning of the study (P>0.05). After intervention, a significant reduction was found in the mean of pain score over time in both Agnogol (P<0.001) and Mefenamic acid (P<0.001) groups, but the difference between two groups was not significant (P>0.05). 
Conclusion: Given the same effect of Agnogol in mitigating dysmenorrhea, we recommend it as an appropriate alternative for Mefenamic acid.

Effect of Cognitive-Behavioral based Stress Management on Anxiety Reduction of Pregnant Women
Nushin Shamsabadi, Dr Afsane Khajevand, Dr Ramezan Hasanzadeh,
Volume 12, Issue 3 (Supplementary 2016)
Abstract

Background and Objective: Pregnancy is often introduced as a stressful experience that may be increased, and leads to some cognitive and behavioral responses called stress. By managing stress in pregnancy period, we can reduce anxiety and prevent from much of obstetric and physical complications. This study aimed to determine the effect of cognitive-behavioral based stress management on anxiety reduction of pregnant women.

Material and Methods: This pretest-posttest quasi-experimental study was conducted on pregnant women referring to health centers in Gorgan city in 2012. Twenty-four patients with eligible criteria were divided randomly into two equal groups of experimental and control. Pre-test was performed by State- trait anxiety inventory and the intervention was administered to experimental group. After that, posttest was taken for both groups. Statistical analysis was performed by covariance.

Results: Analysis of the data shows that pregnant women experience Anxiety. Stress management training in cognitive-behavioral style significantly decrease state- trait anxiety of pregnant women.

Conclusion: Stress management training in cognitive-behavioral style has an effect on state- trait anxiety reduction of pregnant women.


Effect of Maternal Empowerment Training on Frequency of Gastrointestinal Complications in Children Undergoing Chemotherapy
Leila Lashgari, Shamsolmoluk Jalal Manesh , Mohammad Kazem Naeini ,
Volume 18, Issue 2 (7-2021)
Abstract
Background: Given the high prevalence of chemotherapy complications, it is essential to try limiting the side effects in order to prevent reduced quality of life in cancer patients, particularly children. The present study aimed to determine effect of maternal empowerment training on gastrointestinal complications in children undergoing chemotherapy.
Methods: This clinical trial study was performed on mothers with children under 12 years undergoing chemotherapy at the Bahrami Children's Hospital in Tehran (Iran) in 2017. Forty mothers were enrolled in the study via convenience sampling. The subjects were then randomly assigned to an intervention (n=20) and a control group (n=20). Data were collected using a checklist on gastrointestinal complications at baseline and two, four and eight weeks after the last training session. Statistical analysis of data was performed in SPSS 16.
Results: The frequency of gastrointestinal complications reduced significantly after the training in the intervention group (P<0.05). There was no significant difference in the frequency of gastrointestinal complications before and after the intervention in the control group (P>0.05). After the training, the frequency of gastrointestinal complications was significantly lower in the intervention group than in the control group.
Conclusion: The empowerment program could help improve mothers’ knowledge about chemotherapy and associated complications, thereby reducing the frequency of such complications in children undergoing chemotherapy.
 
Maternal stress in the fetal anomaly screening process: A prospective cohort study
Batool Zeidabadi, Abedin Iranpour, Fatemeh Alavi-Arjas, Mohammad Reza Baneshi, Salman Shamsadini Moghadam , Mohammd Moqaddasi Amiri, Mahdiye Taheri,
Volume 21, Issue 3 (10-2024)
Abstract
Background: Fetal health and pregnancy outcomes are significant contributors to increased prenatal stress. The effect of fetal anomaly screening on a mother’s stress is controversial. The present study aimed to explore maternal stress throughout a multi-stage anomaly screening program among healthy pregnant women.
Methods: This prospective cohort study was conducted at the public health centers of Sirjan, Iran from March 2022 to January 2023 using the convenience sampling process. The population included 228 healthy pregnant women. Data were collected using a researcher-made checklist for demographic and obstetrics characteristics. Cohen's Perceived Stress Scale (PSS) was utilized to measure maternal stress at three distinct intervals, including before (weeks 6-10 of pregnancy), during (weeks 11-14 of pregnancy), and after fetal anomaly screening tests (weeks 15-20 of pregnancy). Friedman test was used for measuring the association between maternal stress and fetal abnormality test results. Data were analyzed with Statistical Package for the Social Sciences (SPSS) software version 26 at a significance level of 0.05.
Results: The mothers with higher educational levels (p =0.05, β=1.74), and having a live child experienced lower levels of initial stress (p =0.016, β=2.27). Throughout the time, receiving a normal nuchal translucency (NT) result was associated with a significant decrease in perceived mother's stress (p <0.0001), and abnormal NT ultrasound results (reported in 3.8% of women) led to a rise in the downslope of stress in the third measurement; however, it was not significant.
Conclusion: The present study revealed that maternal stress decreased over time following normal results of fetal anomaly screening. Three factors were associated with lower maternal stress, including university education, having at least a living child, and a normal ultrasound result. Moreover, women at first pregnancy and/or with an abnormal ultrasound result experienced high-stress levels. The findings may be useful in guiding the formulation of health policies and the distribution of resources.
 

The effect of digital coloring on the level of state anxiety and pulse rate in elderly patients before diabetic foot ulcer surgery: A quasi-experimental study
Fatemeh Aramideh , Sepideh Mohammadi , Abbas Shamsalinia , Omolhoda Kaveh ,
Volume 22, Issue 3 (9-2025)
Abstract
Background: Given the anxiety experienced by patients awaiting diabetic foot ulcer surgery, evidence supporting the efficacy of preoperative art therapy can be clinically valuable. However, evidence on the effectiveness of digital coloring, a modern and accessible form of art therapy, remains limited. This study aimed to investigate the effects of digital coloring on state-trait anxiety levels and pulse rate in elderly patients scheduled for diabetic foot ulcer surgery.
Methods: This quasi-experimental study employed a pre-test–post-test design with intervention and control groups. The study was conducted from January 2023 to July 2024 at a referral teaching hospital in Amol, Iran. The participants were selectively assigned to either an intervention group (n=30) or a control group (n=30) via purposive sampling. Both groups received standard preoperative care, but one hour before the scheduled surgery, the intervention group received a one-session digital coloring. Data were collected using a demographic questionnaire and the State-Trait Anxiety Inventory (STAI Form Y-1). The variables were assessed at baseline and immediately after the coloring session in both study groups. An analysis of covariance (ANCOVA) was conducted to compare post-intervention state anxiety between the intervention and control groups, while controlling for pre-intervention anxiety levels. Data analysis in SPSS v25 employed χ², Fisher’s exact, paired, and independent t-tests, with significance set at p <0.05.
Results: Both study groups were homogeneous in terms of gender, age, and education level.  Baseline anxiety (p=0.43) and pulse rate (p=0.12) were similar between groups. Post-intervention results revealed a clinically meaningful reduction in the intervention group (43.20±3.70) versus controls (50.33±6.18), with a significant between-group difference (p<0.001, d=1.42). The between-group difference in pulse rate was also significant (p=0.002), with a large effect size (Cohen’s d=0.87).
Conclusion: Our findings suggest that the digital coloring intervention may be associated with reductions in state anxiety and pulse rate among elderly patients awaiting diabetic foot ulcer surgery. Given that this intervention is simple, inexpensive, and easily accessible, we recommend its use to alleviate state anxiety in clinical settings that typically provoke anxiety, such as during diagnostic procedures.

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